[Asn23] β-Amyloid (1-40), Iowa mutation_product_DataBase

CAS: 374796-72-2 F: C194H296N54O57S W: 4328.82

β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene c

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	[Asn23] β-Amyloid (1-40), Iowa mutation is a biological active peptide. (Several mutations in the beta amyloid precursor gene cause autosomal dominant Alzheimer's Disease in a number of kindreds. The Iowa mutation, where Asp 23 is replaced with Asn, is associated with severe cerebral amyloid beta-protein angiopathy (CAA). The affected individuals share a missense mutation in APP at position 694. The mutated beta-amyloid peptide aggregates more rapidly and forms toxic fibrils.)
Name	[Asn23] β-Amyloid (1-40), Iowa mutation
CAS	374796-72-2
Sequence	Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asn-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val
Shortening	DAEFRHDSGYEVHHQKLVFFAENVGSNKGAIIGLMVGGVV
Formula	C194H296N54O57S
Molar Mass	4328.82
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

PeptideDB